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A molecular model for regulating Rad51 nucleoprotein filament formation by the Swi5-Sfr1 complex. Swi5–Sfr1 stabilizes Rad51 on ssDNA primarily by preventing its dissociation. This stabilization effect leads to a stable nucleating cluster formation and a reduction in filament disassembly. Red half-arrows indicate the kinetic steps affected by SSwi5–Sfr1.

Scientists unraveling the molecular details of DNA recombination regulation

A worldwide group from National Taiwan University (NTU) and Tokyo Tech distinguished how DNA recombinational repair is directed in an ongoing work distributed in...
EM images show sections of single-stranded DNA (ssDNA) being produced instead of double-stranded DNA (dsDNA) in the absence of AND-1. CREDIT Takuya Abe

Unveiling the mechanism protecting replicated DNA from degradation

Scientists at the Tokyo Metropolitan University have successfully depleted AND-1 for DNA replication. They thus able to increase uncommon access to the mechanism behind how...
A research team from the Cancer Science Institute of Singapore at the National University of Singapore, led by Professor Yoshiaki Ito (left), and involving Senior Research Scientist Dr Vaidehi Krishnan (right), has discovered that RUNX proteins play a part in the regulation of DNA repair.

RUNX proteins act as regulators in DNA repair

Humans are constantly exposed to mutagenic DNA damaging lesions called DNA interstrand crosslinks (ICLs) which can be induced by environmental sources such as formaldehyde,...
Conceptual illustration of a droplet containing an artificial neural network made of DNA that has been designed to recognize complex and noisy molecular information, represented as 'molecular handwriting.' Credit: Olivier Wyart

Scientists created AI from DNA

Caltech scientists have recently developed an AI made out of DNA that can tackle a classic machine learning problem by precisely recognizing written by hand...
Quinodoz2017_GraphicalAbstract_v5_b

The cartography of the nucleus

Settled somewhere down in every one of your cells is the thing that appears like a magic trick: Six feet of DNA is bundled...
DNA

Scientist found that the shape of DNA can be changed

The structure of DNA is generally acknowledged to exist as a twofold helix, however extraordinary DNA structures likewise exist. According to a new study...
Using a state-of-the-art type of electron microscopy, an MIT-led team has discovered the structure of an enzyme that is crucial for maintaining an adequate supply of DNA building blocks in human cells

Researchers delivered high-resolution glimpse of enzyme structure

MIT scientists have investigated the enzyme's structure by using a technique called electron microscopy. This new discovery also unveiled the likely mechanism for how cells regulate...
Genetic Study Uncovers Evolutionary History of Dingoes

Genetic Study Uncovers Evolutionary History of Dingoes

A major study of dingo DNA has revealed dingoes most likely migrated to Australia in two separate waves via a former land bridge with...
mars

Scientists have Discovered a Potentially Suicidal Problem with Going to Mars

Nasa wants to have humans on Mars in the next few decades. They are planning human colonies on the Red Planet by the 2030s. Similarly, China...

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