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A random-forest, machine-learning method for identifying copy number variation from exome-sequencing data. A forest of hundreds of decision trees is trained on a validated set of genetic deletions and duplication, the model built from these trees can then be used to accurately identify copy number variation in sample exome-sequencing data. IMAGE: GIRIRAJAN LABORATORY, PENN STATE

New technique can find deletions and duplications in the human genome

Copy number variants (CNVs) are a noteworthy reason for a few genetic disorders, making their identification an essential segment of genetic analysis pipelines. Current...
The approach maps the ones the zeros of digital data to the presence or absence of particular molecules in solutions. The researchers used the scheme to encode image files in solutions.

Researchers store digital images inside molecular thumb drive

Scientists at Brown University have taken a step forward toward storing huge amounts of data in molecular storage systems. The study has shown that...
New method aims to improve match between DNA sample and face database

New method to improve match between DNA sample to a face database

While predicting what someone's face looks like based on a DNA sample remains extremely problematic, it is getting easier to filter the right face...
Harvard Medical School researchers identify new targets to inhibit viral replication and may inform the development of a new class of antiviral drugs. iStock

Catch a virus by the tail

Some RNA viruses such as Segmented negative-sense (SNS) RNA viruses initiate infection by delivering into cells a suite of genomic RNA segments, each sheathed...
Study reveals key step in cell protein production from genes

Study reveals key step in cell protein production from genes

DNA is the information molecule. It stores instructions for making other large molecules, called proteins. These instructions are stored inside each of your cells,...
Scientists created world’s first living organism with fully redesigned DNA

Scientists created world’s first living organism with fully redesigned DNA

Scientists at Cambridge University have created the world’s first living organism that has a fully synthetic and radically altered DNA code. They have replaced the...
Brian Cafferty, a postdoctoral scholar in the lab of George Whitesides

New system that store data in organic molecules for millennia

Although the information is ubiquitous, and its technology arguably among the highest that humankind has produced, its very ubiquity has posed new types of...
April 22, 2019 largest simulation to date of an entire gene of DNA A Los Alamos-led team created the largest simulation to date of an entire gene of DNA, a feat that required one billion atoms to model.

Scientists have created the largest simulation of an entire gene of DNA

The growing interest in the complexity of biological interactions is continuously driving the need to increase system size in biophysical simulations, requiring not only...
Illustration of a DNA-wrapped single-walled carbon nanotube (credit: Benjamin Lambert, EPFL)

Directed evolution method can engineer synthetic nanoparticles

Mimicking natural evolution, directed evolution guides the synthesis of proteins with improved or new functions. The technique is powerful enough that it can engineer...

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