Tag: DNA

Family tree revealing paternal inheritance of mitochondrial DNA (mtDNA). Luo et al.2 sequenced the mtDNA of several members of a family in which many individuals had a high level of mtDNA heteroplasmy (the presence of distinct genetic variants in the same cell). This mtDNA variability is denoted by two colours in the same silhouette of an individual. The analysis showed that some of the individuals with heteroplasmy had inherited mtDNA from both of their parents, breaking the usual pattern of exclusive maternal inheritance of mtDNA. Luo et al. suggest that the ability to inherit paternal mtDNA is a genetic trait.

Mitochondrial DNA can be inherited from fathers, not just mothers

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the...
This DNA tool can help you trace your ancient ancestry

This DNA tool can help you trace your ancient ancestry

Most ancient DNA (aDNA) data were generated through microarrays designed for modern-day populations, which are known to misrepresent the population structure. Past examinations addressed these...
One of the greatest mysteries of DNA replication has been solved

One of the greatest mysteries of DNA replication has been solved

How a critical cellular process is regulated? What that could mean for the future study of genetics? In 1950, Scientists identified DNA replication, but how...
In this Oct. 10, 2018 photo, He Jiankui is reflected in a glass panel as he works at a computer at a laboratory in Shenzhen in southern China's Guangdong province. Chinese scientist He claims he helped make world's first genetically edited babies: twin girls whose DNA he said he altered. He revealed it Monday, Nov. 26, in Hong Kong to one of the organizers of an international conference on gene editing. (AP Photo/Mark Schiefelbein)

Scientist created World’s first genetically edited babies

A Chinese scientist has created the world's first genetically edited babies- twin girls by altering DNA using a new tool capable of rewriting the very blueprint...
In the largest genetic study of Alzheimer's disease, researchers at Washington University School of Medicine in St. Louis and the University of California, San Francisco, have found that genes that increase risk of cardiovascular disease also heighten the risk for Alzheimer’s.

Cardiovascular disease, Alzheimer’s genetically linked

An international team of scientists has identified DNA from almost 1.5 million people and identified points of DNA that appear to be involved both in cardiovascular disease...
Agouti mice. Credit: Randy Jirtle and Dana Dolinoy

Studies question how epigenetic information is inherited

Many studies in recent years have suggested that our eating regimen, our habits or traumatic experiences can have ramifications for the health of our kids...
A molecular model for regulating Rad51 nucleoprotein filament formation by the Swi5-Sfr1 complex. Swi5–Sfr1 stabilizes Rad51 on ssDNA primarily by preventing its dissociation. This stabilization effect leads to a stable nucleating cluster formation and a reduction in filament disassembly. Red half-arrows indicate the kinetic steps affected by SSwi5–Sfr1.

Scientists unraveling the molecular details of DNA recombination regulation

A worldwide group from National Taiwan University (NTU) and Tokyo Tech distinguished how DNA recombinational repair is directed in an ongoing work distributed in...
EM images show sections of single-stranded DNA (ssDNA) being produced instead of double-stranded DNA (dsDNA) in the absence of AND-1. CREDIT Takuya Abe

Unveiling the mechanism protecting replicated DNA from degradation

Scientists at the Tokyo Metropolitan University have successfully depleted AND-1 for DNA replication. They thus able to increase uncommon access to the mechanism behind how...
A research team from the Cancer Science Institute of Singapore at the National University of Singapore, led by Professor Yoshiaki Ito (left), and involving Senior Research Scientist Dr Vaidehi Krishnan (right), has discovered that RUNX proteins play a part in the regulation of DNA repair.

RUNX proteins act as regulators in DNA repair

Humans are constantly exposed to mutagenic DNA damaging lesions called DNA interstrand crosslinks (ICLs) which can be induced by environmental sources such as formaldehyde,...