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A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ Wikipedia

Single-cell RNA profiling

Single-cell RNA sequencing has emerged as an indispensable tool to dissect the cellular heterogeneity and decompose tissues into cell types and/or cell states, which...
MIT researchers have designed nanoparticles that can deliver messenger RNA to specific organs. In this image, lung cells expressing the synthetic mRNA show up as red. Image: Piotr Kowalski

New materials to improve delivery of therapeutic messenger RNA

Messenger RNA, a huge nucleic corrosive that encodes genetic data, can guide cells to create particular proteins. Unlike DNA, mRNA isn't for all time...

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