Researchers alter mRNA therapies for safer immune responses

N1-methylpseudouridylation induces +1 ribosomal frameshifting in mRNA.

The cause of lower back pain

Cedars-Sinai study links back pain to specific spinal cells.

Aging accelerates in transplant patients with older organs

Alzheimer's polygenic risk scores tied to different processes based on cell type.

Nerve stimulation boosts pancreas regeneration of insulin cells

Vagal nerve optogenetics boosts glucose-stimulated insulin secretion and β cell growth.

Anthrobots: Tiny biological robots from human cells

The multicellular bots move around and help heal “wounds” created in cultured neurons.

Harnessing a parasite’s power to halt pain

Leishmania mexicana induces metabolomic shifts to reduce pain in skin lesions.

UCLA unravels aggressive growth in prostate cancers, eluding treatment

Temporal evolution reveals dual lineages in prostate cancer transformation.

A cell signaling pathway regulates melanoma cell metastasis to the brain

The pathway changes the gene expression pattern of melanoma cells.

Restoring nerve cells: Healing after injury and in chronic disease

Mitf, a Schwann cell sensor of axonal integrity, drives nerve repair.

Yale researchers uncover the process of accurate RNA splicing

Structural exploration of intron catalysis and dynamics in the splicing process.

Restoring youth to COVID-19 affected brains

Alleviating brain aging and COVID-19 pathology with senolytic therapy.

UC Irvine-led study discovers novel cause of brain hemorrhage

In vivo microhemorrhages linked to erythrocyte-brain endothelial interactions.

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