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Alzheimer's disease destroys neurons that keep us awake

Alzheimer’s disease destroys neurons that keep us awake

A study suggests Tau tangles, not amyloid plaques, drive daytime napping that precedes dementia.
Neurons in the hippocampus, a brain region for learning and memory, that is impaired already at early stages of Alzheimer´s disease. Image: Y. Zhang und A. Konnerth / TUM

Direct toxic action of beta-amyloid identified

Scientists have identified early cellular dysfunction in Alzheimer's patients who have already developed clinical symptoms contain large clumps of the protein beta-amyloid, known as plaques.
A new blood test for early detection of Alzheimer’s disease

A new blood test for early detection of Alzheimer’s disease

Alzheimer's is the most common cause of dementia that causes problems with memory, thinking, and behavior. The disease accounts for 60% to 80% of...
Blood pressure device

Common blood pressure pill could slow down Alzheimer’s

While searching for the treatments that slow down the progression of Alzheimer's, scientists discovered that the common blood pressure drug nilvadipine might hold the...
brain

Biggest ever map of human Alzheimer’s brain published

Scientists at the The University of Manchester have created the largest ever dataset of differences between healthy brains and those with Alzheimer’s Disease. Moreover, scientists also...
Image of P. gingivalis' gingipains in the neurons of Alzheimer's brain. P. gingivalis gingipains = red, neurons = yellow, astrocytes = green. Credit: Cortexyme, Inc.

Scientists may finally know what causes Alzheimer’s

A team of international scientists led by Cortexyme, Inc., a privately held, the clinical-stage pharmaceutical company has recently discovered the role of a common bacterium, Porphyromonas...
Antipalaptic drugs are associated with accumulation of hospital days in people with Alzheimer's disease

Antipalaptic drugs are associated with accumulation of hospital days in people with Alzheimer’s disease

Antiepileptic drugs (AEDs) are as often used among more seasoned people and particularly among those with Alzheimer's disease. Although the essential sign for AED...
Alzheimer's is not one disease but six different conditions

Alzheimer’s is not one disease but six different conditions

A new study that involves 19 researchers from several institutions, has suggested a new way to classify patients with Alzheimer's disease. The study suggests that Alzheimer's,...
Strong painkillers can cause hip fracture in Alzheimer’s patients

Strong painkillers can cause hip fracture in Alzheimer’s patients

A new study by the University of Eastern Finland shows that people using strong painkillers, opioids have double the risk of hip fracture contrasted with...

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