Alzheimer’s

Aging accelerates in transplant patients with older organs

Alzheimer's polygenic risk scores tied to different processes based on cell type.

Protein clumps can cause brain diseases

Prion protein cross-seeding deactivates TDP-43.

Neuroinflammation’s key role in Alzheimer’s revealed

The results have important implications for the design of microglia-centered therapeutics for AD.

Restoring youth to COVID-19 affected brains

Alleviating brain aging and COVID-19 pathology with senolytic therapy.

UC Irvine-led study discovers novel cause of brain hemorrhage

In vivo microhemorrhages linked to erythrocyte-brain endothelial interactions.

New study sheds light on how Alzheimer’s tau tangles begin

Inhibition of GCPII lowers pT217Tau in the brains of aged macaques.

Elevated metabolism as an Alzheimer’s indicator

Early mitochondrial hypermetabolism in Alzheimer's mice.

Unexpected ties: Sleep, brain insulation, and neurodegeneration

BMAL1 loss in oligodendroglia impacts myelination and sleep.

Mild cognitive impairment goes undiagnosed in 7 Million Americans

Uncovering undiagnosed cognitive impairment in the U.S. Medicare population.

Münster University’s study of nanomachines in peroxisomal processes

Unveiling the peroxisomal Pex1/Pex6 ATPase complex with substrate.

Understanding how signaling proteins stop inflammation

MKK6-p38α complex: Defining MAPK activation.

Age-related blood cell mutations protect against Alzheimer’s disease

Stem-ing the tide of Alzheimer’s.

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