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Image showing DYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric developmental and functional disorders.
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Protein interactions unveil molecular insights into Down syndrome

Dr. Prajakta Banik

FAM53C identified as a binding partner inhibiting DYRK1A kinase.

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