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A random-forest, machine-learning method for identifying copy number variation from exome-sequencing data. A forest of hundreds of decision trees is trained on a validated set of genetic deletions and duplication, the model built from these trees can then be used to accurately identify copy number variation in sample exome-sequencing data. IMAGE: GIRIRAJAN LABORATORY, PENN STATE

New technique can find deletions and duplications in the human genome

Copy number variants (CNVs) are a noteworthy reason for a few genetic disorders, making their identification an essential segment of genetic analysis pipelines. Current...
Atypical eating behaviors may be a new diagnostic indicator for autism

Atypical eating behaviors may be a new diagnostic indicator for autism

Atypical eating behavior may include severely limited food preferences, hypersensitivity to food texture or temperatures, and pocketing food without swallowing. Such action is a...
Gluconate, a small organic molecule, inhibits neonatal seizures in rodent models and could open up new avenues for the treatment of epilepsy in human newborns. The image illustrates the structure of neonatal hippocampus (green), overlaid with a typical electrophysiological trace of seizure activity, and the molecular structure of gluconate. IMAGE: CHEN LABORATORY, PENN STATE

A new drug that inhibits neonatal seizures

Neonatal seizures or neonatal convulsions are epileptic fits occurring from birth to the end of the neonatal period. The neonatal period is the most...
male office workers spy on female colleagues laptop

Study finds Wi-Fi location affects online privacy behavior

The speed of technology has far outpaced the security of the technology. For example, free public wireless connections have always left users vulnerable to...
Tied atery

Everyday stress may boost blood vessel dysfunction in people with depression

Long term stress, or a constant stress experienced over a prolonged period of time, can contribute to long-term problems for heart and blood vessels....
Psychology may help explain why male and female serial killers differ

Psychology may help explain why male and female serial killers differ

A recent study has found that male serial killers and female serial killers choose their victims and commit crimes in different ways. Male serial...
After being immunized with the proteins, rabbits developed antibodies that were able to bind with the virus. IMAGE: © GETTYIMAGES MIRROR-IMAGES

Custom-made proteins may help create antibodies to fight HIV

HIV, the virus that causes AIDS, is one of the world’s most serious public health challenges and it still continues to be a major...
Plastic dome coated with a new antireflection coating (right), and uncoated dome (left). IMAGE: GIEBINK LAB/PENN STATE

Antireflection coating makes plastic invisible

Scientists at the Penn State have developed a new type of Antireflection coating that could potentially improve existing coatings to the extent that it can make...
This image, taken with Hubble's Wide Field and Planetary Camera 2in 1995, shows the orange-red rings surrounding Supernova 1987A in the Large Magellanic Cloud. The glowing debris of the supernova explosion, which occurred in February 1987, is at the center of the inner ring. The small white square indicates the location of the STIS aperture used for the new far-ultraviolet observation.

How hot are atoms in the shock wave of an exploding star?

Scientists at the Penn State have developed a new technique to measure the temperature of atoms during the explosive death of a star. Scientists combined...

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