Wednesday, March 29, 2023

DNA

How genome doubling helps cancer development

WGD changes DNA structure, activating oncogenes that drive cancer growth.

Telomere shortening is linked to signs of Alzheimer’s in brain scans

The length of the telomeres which cap chromosomes is associated with a reduced risk of dementia, but not stroke or Parkinson’s

Lack of immunological response is associated with COVID-19 severity

Obesity increases susceptibility to COVID-19.

Largest-ever genetic study revealed genetic regions associated with endometriosis

The study found new data about the variants that increase the risk of the disease.

Study highlights how amino acids shaped the genetic code of ancient microorganisms

Scientists gain insights into how amino acids shaped the genetic code of ancient microorganisms.

Identifying a processor route for DNA damage from next-generation cancer treatment

POLQ repairs complex DNA double-strand breaks induced by heavy ionirradiation.

Existing microbiome analyses have significant flaws, the study

This study reveals intrinsic constraints in metagenomic analysis stemming from current database limitations.

Study figured out what ancient humans might have been able to smell

Duke lab built Neanderthal and Denisovan smell receptors and tested them in a dish.

Investigating the genetics of heart attacks and strokes in Hispanics

The research is possible thanks to a $2.5 million grant from the National Heart Lung and Blood Institute.

The red junglefowl – the wild ancestor of the chicken – is losing its genetic diversity

DNA from domesticated chickens is tainting genomes of wild red junglefowl

Why do older fathers pass on more genetic mutations to their offspring?

The mechanisms that might underlie these well-documented trends have long remained a mystery.

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