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A T cell, here in violet, makes contact with a transplant organ cell, here in brown and purple. The T cell secretes the enzyme granzyme B, here in gray, which attacks the organ cell. But granzyme B also severs fluorescent signal molecules, in green, from the rejection detecting nanoparticle, in light red. The signal molecules makes their way into the urine, where they give off a fluorescent cue.

Urine test detects organ transplant rejection

The early detection of the onset of transplant rejection is critical for the long-term survival of patients. The diagnostic gold standard for detecting transplant...