TOPICSCRISPR

CRISPR

Genetic engineering
Biology

Cutting DNA like never before: A new tool for single-stranded targeting

Pranjal Malewar

A new family of enzymes capable of inducing targeted cuts in single-stranded DNA.

Person in protective gear spraying pesticides in a crop field highlighting agricultural pest management practices
Technology

New powerful technology reverses insecticide resistance in pests

Jay Kakade

Since insecticides are the most prevalent way of controlling crop damage from pests, their overuse has rendered pests insecticide-resistant. When beetles, moths, or other...

Health

Researchers discover flavivirus spread mechanism

Dr. Prajakta Banik

Effective treatments for Flaviviridae viruses, like dengue, are needed since no specific medications are available.

Image showing SHINE, a rapid diagnostic test developed by Pardis Sabeti's lab in 2020, uses paper strips and CRISPR enzymes to identify specific sequences of viral RNA in samples.
Health

Easy flu tests may enhance diagnosis and tracking

Dr. Prajakta Banik

CRISPR assays for quick flu detection and subtyping.

Unveiling the mysteries of cell division in embryos with timelapse photography
Biology

Unveiling the mysteries of cell division in embryos

Pranjal Malewar

They lay a new foundation for elucidating embryonic mitosis.

Pipette on multi well plate over dna research data
Health

Genetic tool tracks CRISPR editing risks

Dr. Prajakta Banik

Deciphering DNA repair progression with mutation classifier.

avatar freepik 6.05m assets Follow 3d representation of dna
Biology

Understanding the wiring of the human genome

Pranjal Malewar

Being able to understand which genes these mutations impact is really critical.

Deoxyribonucleic acid
Biology

Faster, cheaper creation of synthetic chromosomes by researchers

Dr. Prajakta Banik

Creating synthetic chromosomes from natural DNA.

Free photo biotechnology specialist in the laboratory conducting experiments
Biology

Scientists discovered thousands of rare new CRISPR systems

Pranjal Malewar

These systems that have a range of functions and could enable gene editing, diagnostics, and more.

Image showing red blood cells
Health

Enhancing CAR T cells for blood cancer treatment

Dr. Prajakta Banik

Epitope editing for universal blood cancer immunotherapy.

Image showing pigmentation
Biology

Scientists uncover 135 novel genes controlling skin pigmentation

Dr. Prajakta Banik

Revealing the factors behind human pigmentation: Genome-wide genetic search.

Image showing Pictured is a Cryo-EM map of a Fanzor protein.
Biology

CRISPR-like system in animals helps in treating human diseases

Dr. Prajakta Banik

Fanzor could revolutionize gene therapy.

DNA Damage
Biology

Antioxidant enzymes repair DNA damage

Pranjal Malewar

In crisis, the nucleus calls antioxidant enzymes to the rescue.

Health

A gene-editing technology could help to accelerate cancer mutations

Vidya Nagalwade

Scientists can develop new drugs to target cancer mutations.

Spinal cord astrocytes
Health

CRISPR-Cas13 targets proteins causing ALS and Huntington’s disease

Pranjal Malewar

A single genetic mutation can have profound consequences.

Ultrasound irradiation
Health

CRISPR/Cas9 gene-editing increases the effectiveness of ultrasound cancer therapy

Pranjal Malewar

Study lays the foundation for the widespread application of CRISPR/Cas9 with promising clinical translation.

Image showing DNA editing
Science

Using gene-editing to create single-sex mice litters

Pranjal Malewar

The technology could be used to improve animal welfare in scientific research and perhaps also agriculture.

Image showing mosquito
Health

A new system that restrains populations of mosquitoes

Pranjal Malewar

CRISPR-based system developed to safely restrain mosquito vectors via sterilization.

CasMINI
Science

An efficient, mini CRISPR system engineered

Pranjal Malewar

Its diminutive size should make it easier to deliver into human cells, tissues and the body for gene therapy.

Watching DNA structural changes in real-time!
Science

Watching DNA structural changes in real-time!

Pranjal Malewar

A novel CRISPR-based genome labeling scheme for reliable visualization of genomic elements in living cells.

Gene editing could stop virus transmission in cells
Health

Gene editing could stop virus transmission in cells

Pranjal Malewar

Discovery points to targeted treatment for COVID-19.

CRISPR/Cas9 genome editing in space demonstrated for the first time
Space

CRISPR/Cas9 genome editing in space demonstrated for the first time

Amit Malewar

A novel method for studying how cells repair damaged DNA in space.

Scientists at TUM have created chickens and pigs with integrated genetic scissors. This can be used at all stages of the animals' development. They have already demonstrated applications in chicken embryos (image) as well as in living pigs
Science

Scientists created chickens and pigs with integrated genetic scissors

Amit Malewar

Genome editing in farm animals.

The CRISPR-SNP-Chip device uses CRISPR molecules and graphene transistors to detect target single-point-mutations in DNA samples. (Photo courtesy of Cardea Bio).
Health

New hand-held device to detect point mutations in sickle cell and ALS diseases

Pranjal Malewar

CRISPR-Chip advance streamlines genetic testing for medical diagnostics and research.

Perturb-Seq method
Health

A new technique for investigating autism spectrum disorder

Pranjal Malewar

Scientists apply ‘Perturb-Seq’ method to a living organism for the first time.

SunTag split-sfGFP CRISPR system
Science

A novel CRISPR-based genome labeling scheme

Pranjal Malewar

Reliably visualizing genomic elements in living cells.

Scientists expanded the Capabilities of CRISPR gene editing technique
Technology

Scientists expanded the Capabilities of CRISPR gene editing technique

Ashwini Sakharkar

CRISPR-Cas9, which is short for clustered, regularly interspaced short palindromic repeats and CRISPR-associated protein 9. The technique is faster, cheaper, more accurate, and more...

Fruit flies with mutated antimicrobial peptides (red eyes) let bacteria (green) grow out of control, while normal flies suppress the infection. Credit: Mark Austin Hanson, EPFL
Science

CRISPR reveals the secret life of antimicrobial peptides

Amit Malewar

Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring molecules that are produced as a first line of defense by all...

CRISPR technique can help you prevent from getting obese
Health

CRISPR technique can help you prevent from getting obese

Pranjal Malewar

Scientists recently made an exciting discovery suggesting that CRISPR therapies can prevent obesity without cutting or editing a DNA. The study- conducted by the UC San...

Scientists Have Encoded a Movie Into The DNA of Living Bacteria
Technology

Scientists Have Encoded a Movie Into The DNA of Living Bacteria

Amit Malewar

For the first ever time, scientists at the Harvard University have encoded a movie into the DNA bacteria. While scientists have previously set the...

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