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Non-toxic water-repellent breakthrough to replace synthetic chemicals

The unique ‘bulky’ attribute of fluorine can actually be replicated in a different, non-toxic form.

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For decades, synthetic chemicals such as PFAS (perfluoroalkyl) have been a staple in countless everyday products. From water-repellent coatings to grease-resistant packaging, PFAS have found their way into our lives. Yet, these same chemicals pose significant risks to human health and the environment.

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At the heart of their effectiveness lies fluorine, a unique element that creates an impermeable barrier against substances like air and water. For years, fluorine’s properties were deemed irreplaceable—until now.

A collaborative team of scientists from the UK, Japan, and France set out to challenge this assumption. Through meticulous research, they unearthed a safer alternative for synthetic chemicals, called PFAS (perfluoroalkyl substances).

Their study dove deep into the chemical structure of PFAS, seeking a way to mimic this fluorine’s bulkiness without its toxic footprint. The answer? Non-toxic components are made entirely of carbon and hydrogen.

The scientists found inspiration in unlikely places. By examining “bulky” fragments in everyday chemical systems like fats and fuels, they crafted modified substances that maintained fluorine’s beneficial characteristics without harmful consequences.

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Over ten years, this process involved state-of-the-art chemical synthesis techniques to replace fluorine with safer carbon—and hydrogen-based groups.

Given PFAS’s extensive use across industries, the breakthrough has far-reaching implications. From textiles and non-stick cookware to firefighting foams, the potential to replace these harmful chemicals with eco-friendly alternatives is monumental.

Now, the team is focused on turning their lab discoveries into commercially viable solutions. Their work has captured the attention of industrial and academic researchers alike, signaling a transformative step toward safer, sustainable materials.

Journal reference:

  1. Masanobu Sagisaka, Thierry Darmanin, Frederic Guittard et al. New fluorine-free low surface energy surfactants and surfaces. Journal of Colloid and Interface Science. DOI: 10.1016/j.jcis.2025.03.018
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