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Science Translational Medicine

Targeting leukemia stem cells

Acute myeloid leukemia (AML) is a severe cancer of the blood and bone marrow, often fatal. The disease is driven by leukemic stem cells...

Clear experimental skull implant may enable functional ultrasound imaging of the brain for patients with serious head injuries.

New brain imaging technique uses a transparent window in patient’s skull

Functional ultrasound imaging can record brain activity through a transparent skull implant.

Bald man battles cancer

Noninvasive chemobrain therapy

Gamma entrainment alleviates chemo-induced cognitive decline.

Mri of the head and brain close up

New imaging reveals brain’s hidden cells

Advancements in immunostaining for brain nanostructures.

A man holds his head in front of the pills

Fast antidepressants and positive neuropsychological effects

Antidepressants swiftly alter emotional bias in rats, a new study shows.

First aid in the hospital sick male patient sleeps on the bed

A fundamental mechanism that controls the body’s response to limited oxygen

A shared genetic trait that could predict a higher risk of small lung vessel disease.

Man suffering from back pain at workplace bad posture problem

The cause of lower back pain

Cedars-Sinai study links back pain to specific spinal cells.

Senior male asian suffering from bad pain in his chest heart attack at home

RNA fragment’s promise in atherosclerosis therapy

Targeting microRNA repressors reduces atherosclerosis in mice.

Small experimental mouse is on the laboratory researcher's hand

Stanford study boosts aging mice with nerve-muscle restoration

Blocking 15-PGDH gerozyme for nerve-muscle regeneration.

Microbiology laboratory test in scientist hand on background

MRSA and superbugs face defeat with unique vaccine

Protein-free vaccine boosts innate immunity and guards against hospital infections.

Image showing liver

Protein-causing liver damage could be a new focus for treatment

The role of CYR61 in liver damage and NASH Fibrosis.

Image showing red blood cells

Enhancing CAR T cells for blood cancer treatment

Epitope editing for universal blood cancer immunotherapy.

Image showing covid-19 vaccine

An inhalable COVID vaccine that successfully protects against the virus

A study shows that a shot is not necessary for providing protection.

Image showing man coughing

Discovery of a new therapeutic target for ARDS

Rejuvenating blood vessels: The role of endothelial FoxM1 in healing lungs.

Image showing girl having pain in abdomen

Gene therapy offers promise to children battling kidney disease

Gene therapy halts kidney disease in nephrotic syndrome.

Image showing cell multiplication

COVID-19 causes mitochondrial dysfunction in the heart and other organs

These findings suggest new approaches for treating COVID-19.

Image showing superbug

New antibiotic shows promise against drug-resistant superbugs

LPC-233: A new antibiotic against drug-resistant bacteria.

Image showing side-view-man-wearing-hearing-aids.

Hearing restoration: New hope for people with hearing loss

Gene therapy restores hearing in adult mice through cerebrospinal fluid.

neurons in the brain

Cells that are particularly susceptible to Alzheimer’s are identified

Scientists identified a subset of neurons within this body that are most susceptible to neurodegeneration.

low white blood cell counts

Brain cancer patients may benefit from treatment to boost white blood cells

Blocking immune suppressor cells in mice with glioblastoma improved survival.

Image showing electrocardiogram

Serotonin can impact the mitral valve of the heart, the study

The link between serotonin and heart valve disease.

Image showing a woman tasting her sense of smell

Why loss of smell occurs in long COVID-19?

The inflammatory mechanism could also help explain other long COVID-19 symptoms.

98 percent effective in blocking sperm

A new way to prevent pregnancy without side effects

Non-hormonal gel proves effective at helping mucus block sperm.

human gastroesophageal junction

Scientists generated a lab-grown human tissue model for food tube cancer

A potential therapeutic target for gastroesophageal junction cancer.

triple-negative breast cancer

Scientists identify novel molecular biomarkers in cells that spread a deadly form of breast cancer

The study could pave the way for developing new treatments that target such molecular variations.

COVID thrombo inflammation blood vessel with clot and antibodies

Scientists identified the cause of COVID-19 blood clots

A new study reveals the virus triggers antibodies circulating through the blood, causing clots in people hospitalized with the disease.

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