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Science Translational Medicine

Health

Targeting leukemia stem cells

Dr. Prajakta Banik

Acute myeloid leukemia (AML) is a severe cancer of the blood and bone marrow, often fatal. The disease is driven by leukemic stem cells...

Clear experimental skull implant may enable functional ultrasound imaging of the brain for patients with serious head injuries.
Health

New brain imaging technique uses a transparent window in patient’s skull

Ashwini Sakharkar

Functional ultrasound imaging can record brain activity through a transparent skull implant.

Bald man battles cancer
Health

Noninvasive chemobrain therapy

Dr. Prajakta Banik

Gamma entrainment alleviates chemo-induced cognitive decline.

Mri of the head and brain close up
Health

New imaging reveals brain’s hidden cells

Dr. Prajakta Banik

Advancements in immunostaining for brain nanostructures.

A man holds his head in front of the pills
Health

Fast antidepressants and positive neuropsychological effects

Dr. Prajakta Banik

Antidepressants swiftly alter emotional bias in rats, a new study shows.

First aid in the hospital sick male patient sleeps on the bed
Biology

A fundamental mechanism that controls the body’s response to limited oxygen

Pranjal Malewar

A shared genetic trait that could predict a higher risk of small lung vessel disease.

Man suffering from back pain at workplace bad posture problem
Health

The cause of lower back pain

Dr. Prajakta Banik

Cedars-Sinai study links back pain to specific spinal cells.

Senior male asian suffering from bad pain in his chest heart attack at home
Health

RNA fragment’s promise in atherosclerosis therapy

Dr. Prajakta Banik

Targeting microRNA repressors reduces atherosclerosis in mice.

Small experimental mouse is on the laboratory researcher's hand
Health

Stanford study boosts aging mice with nerve-muscle restoration

Dr. Prajakta Banik

Blocking 15-PGDH gerozyme for nerve-muscle regeneration.

Microbiology laboratory test in scientist hand on background
Health

MRSA and superbugs face defeat with unique vaccine

Dr. Prajakta Banik

Protein-free vaccine boosts innate immunity and guards against hospital infections.

Image showing liver
Health

Protein-causing liver damage could be a new focus for treatment

Dr. Prajakta Banik

The role of CYR61 in liver damage and NASH Fibrosis.

Image showing red blood cells
Health

Enhancing CAR T cells for blood cancer treatment

Dr. Prajakta Banik

Epitope editing for universal blood cancer immunotherapy.

Image showing covid-19 vaccine
Health

An inhalable COVID vaccine that successfully protects against the virus

Vidya Nagalwade

A study shows that a shot is not necessary for providing protection.

Image showing man coughing
Health

Discovery of a new therapeutic target for ARDS

Dr. Prajakta Banik

Rejuvenating blood vessels: The role of endothelial FoxM1 in healing lungs.

Image showing girl having pain in abdomen
Health

Gene therapy offers promise to children battling kidney disease

Dr. Prajakta Banik

Gene therapy halts kidney disease in nephrotic syndrome.

Image showing cell multiplication
Health

COVID-19 causes mitochondrial dysfunction in the heart and other organs

Pranjal Malewar

These findings suggest new approaches for treating COVID-19.

Image showing superbug
Health

New antibiotic shows promise against drug-resistant superbugs

Dr. Prajakta Banik

LPC-233: A new antibiotic against drug-resistant bacteria.

Image showing side-view-man-wearing-hearing-aids.
Health

Hearing restoration: New hope for people with hearing loss

Dr. Prajakta Banik

Gene therapy restores hearing in adult mice through cerebrospinal fluid.

neurons in the brain
Health

Cells that are particularly susceptible to Alzheimer’s are identified

Amit Malewar

Scientists identified a subset of neurons within this body that are most susceptible to neurodegeneration.

low white blood cell counts
Health

Brain cancer patients may benefit from treatment to boost white blood cells

Pranjal Malewar

Blocking immune suppressor cells in mice with glioblastoma improved survival.

Image showing electrocardiogram
Health

Serotonin can impact the mitral valve of the heart, the study

Pranjal Malewar

The link between serotonin and heart valve disease.

Image showing a woman tasting her sense of smell
Health

Why loss of smell occurs in long COVID-19?

Pranjal Malewar

The inflammatory mechanism could also help explain other long COVID-19 symptoms.

98 percent effective in blocking sperm
Health

A new way to prevent pregnancy without side effects

Pranjal Malewar

Non-hormonal gel proves effective at helping mucus block sperm.

human gastroesophageal junction
Health

Scientists generated a lab-grown human tissue model for food tube cancer

Pranjal Malewar

A potential therapeutic target for gastroesophageal junction cancer.

triple-negative breast cancer
Health

Scientists identify novel molecular biomarkers in cells that spread a deadly form of breast cancer

Pranjal Malewar

The study could pave the way for developing new treatments that target such molecular variations.

COVID thrombo inflammation blood vessel with clot and antibodies
Health

Scientists identified the cause of COVID-19 blood clots

Pranjal Malewar

A new study reveals the virus triggers antibodies circulating through the blood, causing clots in people hospitalized with the disease.

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