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Molecular Psychiatry

Young autistic boy playing with toys at home
Neuroscience

UNIGE scientists uncovered the brain circuit behind Autism-related social challenges

Amit Malewar

Autism: the neural origin of the social bound.

Young woman
Health

CU Anschutz researchers unravel antidepressant mechanism

Dr. Prajakta Banik

The neuroplasticity perspective on depression.

Traumatised frustrated stressed depressed man
Health

Testosterone’s role in anxiety unveiled

Dr. Prajakta Banik

Hippocampal TACR3, testosterone, and anxiety synapses.

Woman builds tower of wooden blocks
Health

New gene found to protect against Parkinson’s disease

Dr. Prajakta Banik

Natural SHLP2 variant protects against Parkinson's disease.

Image showing Romo-Nava said if proven effective, further research will explore the optimal dose, frequency and conditions spinal cord stimulation can be used .
Health

New study suggests spinal cord stimulation for depression treatment

Dr. Prajakta Banik

Pilot trial explores noninvasive spinal stimulation for major depression.

Elderly man drinking cup of coffee
Health

Elevated metabolism as an Alzheimer’s indicator

Dr. Prajakta Banik

Early mitochondrial hypermetabolism in Alzheimer's mice.

Image showing The study findings suggest that when the proteins don’t bind properly, signaling among neurons, illustrated above, becomes imbalanced, which can lead to related negative behavioral symptoms.
Health

Unexpected link between schizophrenia risk proteins

Dr. Prajakta Banik

Controlling fast-spiking neurons: Cytoskeleton-membrane interaction.

Image showing brain mechnism.
Neuroscience

Mouse Hoxb8 microglia stimulation induces anxiety and grooming in specific brain regions

Vidya Nagalwade

Chronic anxiety and OCSD-like behavior in mice.

insights into the importance of a minor cell type in the brain
Neuroscience

Study uncovers brain mechanism that activates anxiety and OCSD behaviors

Pranjal Malewar

This work is unique and has challenged the current dogma.

Alcoholism
Science

Even small quantities of alcohol causes significant changes in brain circuitry

Amit Malewar

How many drinks is too many?

Image showing alcohol in two glasses with ice
Health

The study offers evidence that alcohol accelerates biological aging

Pranjal Malewar

It has been less certain whether alcohol also accelerates the aging process.

Claudio Soto
Health

Whole blood exchange could offer disease-modifying therapy for Alzheimer’s

Pranjal Malewar

This approach has the advantage that the disease can be treated in the circulation instead of in the brain.

One of the two X-chromosomes is randomly selected and inactivated in the early embryonic stage in females (X-chromosome inactivation). Credit: Katsuhiko Tabuchi, Shinshu University, Japan
Science

Looking behind a rare brain disease for clues to treat more common mental disorders

Amit Malewar

Mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH) is an X-linked disorder affecting females and characterized by severe intellectual disability, microcephaly, and...

Alzheimer's is not one disease but six different conditions
Science

Alzheimer’s is not one disease but six different conditions

Pranjal Malewar

A new study that involves 19 researchers from several institutions, has suggested a new way to classify patients with Alzheimer's disease. The study suggests that Alzheimer's,...

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