When we need to recharge, we often go on vacations or relax at spas. But what if we could recharge our cells to help fight aging and diseases? As we age or face illnesses, our cells, especially the mitochondria, which are the cell’s powerhouses, become less able to recharge.
When mitochondria don’t work well, we feel tired, our tissues can degenerate, and we age faster. Everyday activities can take much longer to recover, showing how vital mitochondria are for our health.
Most current treatments for aging-related diseases, like type 2 diabetes and Alzheimer’s, focus on relieving symptoms. However, there is hope on the horizon.
Researchers at Texas A&M are pioneering a new approach, using nanotechnology to enhance mitochondrial function. This innovative method could potentially revolutionize the way we treat these diseases.
Under the leadership of Dr. Kanwar Abhay Singh at Texas A&M, a team of researchers has come together to tackle this challenge. They have created special nanoparticles called molybdenum disulfide (MoSâ‚‚) nanoflowers, named for their flower-like shape.
The tiny particles can help regenerate mitochondria, the energy producers in our cells, by stimulating them to create more energy. The findings suggest that these nanoflowers could lead to new treatments for diseases like muscle dystrophy, diabetes, and neurodegenerative disorders by increasing cell energy production.
Researchers highlighted that this research could help extend healthy lifespans and improve patient outcomes with age-related diseases. Other collaborators have also played a crucial role in understanding how these nanoflowers enhance mitochondrial function and cellular energy.
Researchers explained that by using advanced computer tools, they can understand how cells react to new nanomaterials, which could lead to better medical treatments. This process helps cells get instructions to repair their energy producers, called mitochondria.
The team’s next step is to find a way to deliver these nanoflowers into human tissues for potential medical use. According to researchers, small details in research, like tiny changes in nanomaterials, can lead to important discoveries that help solve major health issues.
Journal reference :
- Singh, K.A., Soukar, J., Zulkifli, M. et al. Atomic vacancies of molybdenum disulfide nanoparticles stimulate mitochondrial biogenesis. Nature Communications. DOI: 10.1038/s41467-024-52276-8.
