Binding break: join in or not?

Excitation with a laser beam does not affect the efficiency of a chemical exchange reaction.


Nucleophilic substitution is a commonly used reaction in organic chemistry. It assumes an imperative part in the synthesis of new compounds or biomolecules in solution and is in this way of extraordinary mechanical significance. In the response, charged particles hit atoms and one sub-atomic gathering is supplanted by another.

For quite a while, science has been endeavoring to reproduce and comprehend these procedures at the interface of chemistry and physics at the nuclear level in the research center. The group headed by trial physicist Roland Wester at the Institute of Ion Physics and Applied Physics at the University of Innsbruck is one of the world’s driving examination gatherings.

In a uniquely developed test, the physicists from Innsbruck impact the accused particles of atoms in a vacuum and look at the response items. To decide whether focused on vibration excitation affects a substance response, researchers utilize a laser shaft that vibrates a locale of the atom. In the present test, adversely charged fluorine particles (F – ) and iodomethane atoms (CH 3I) utilized.

In the crash, because of the trading of iodine bond by a fluorine bond, a fluoromethane atom, and an adversely charged iodine molecule are framed. Prior to the particles meet, the laser energies in the atom extending vibrations of the hydrogen-carbon compounds.

Participating scientist Jennifer Meyer said, “Our measurements show that the laser excitation does not increase the exchange reaction. The result is substantiated by the observation that a competitive reaction is strongly increasing. In the process, a hydrogen atom is torn from the iodomethane molecules and a hydrogen fluoride (HF) is formed.”

“We let two particles collide 20 times per second, and the laser is used every second time. And we repeat that millions of times, “explains Meyer. “Whenever the laser is irradiated, this proton exchange reaction is dramatically enhanced.”

Roland Wester said, ‘The system that we are now studying is so large that observers first appeared. But it is still small enough to be able to study these observers very precisely.”

“Important for the application is also the question of whether certain reactions can be intensified by the targeted excitation of individual molecule groups. If you understand something, you can also exercise control.”

Jennifer Meyer said, “Instead of stimulating a reaction through heat, it may make sense to stimulate only individual groups of molecules to achieve a specific reaction. This may avoid competing for reaction processes that are a common problem in industrial chemistry or biomedical research. The better the control over the chemical reaction, the less waste is produced and the lower the costs.”

The current publication has been published in the journal Science Advances.

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